There are not specifically better choices to bet on, given that the odds are very close. The minor exception are numbers 3 and 18, where the house edge is the lowest (3.79% compared to 3.97% for numbers 4 to 17). This is because these numbers can only be thrown one way. The chances of these numbers falling are slightly lower, but a correct guess can result in winnings of up to 1,000 times your stake.